EXPOSED AND SEQUESTERED ANTIGENS IN TESTES AND THEIR PROTECTION BY REGULATORY T CELL-DEPENDENT SYSTEMIC TOLERANCE

Exposed and Sequestered Antigens in Testes and Their Protection by Regulatory T Cell-Dependent Systemic Tolerance

Continuous exposure of tissue antigen (Ag) to the autoantigen-specific regulatory T cells (Treg) is required to maintain Treg-dependent systemic tolerance.Thus, testis autoantigens, previously considered as sequestered, may not be protected by systemic tolerance.We now document that the complete testis antigen sequestration is not valid.The haploid

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Adult-Onset Type 1 Diabetes and Pregnancy: Three Case Reports

From 5% to 10% of diabetic patients have type 1 diabetes.Here we describe three cases of adult-onset type 1 diabetes in pregnancy treated at our clinic between 2009 and 2012.Two patients came for specialist examination during pregnancy, the third after pregnancy.These women had no click here prior overt diabetes and shared certain characteristics,

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Utility of Digital Breast Tomosynthesis with Two-Dimensional Synthesized Mammography Images: A Pictorial Essay

Background Mammography has been established read more as the key modality in the detection and diagnosis of breast cancers.Digital breast tomosynthesis (DBT) has emerged as a mammographic technique which allows improved visualization of abnormalities by reducing the effect of overlapping breast tissue.Purpose This article is a pictorial essay which

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